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COBEM 2023

27th International Congress of Mechanical Engineering

ASSESSMENT OF HEALTH PARAMETERS FOR AN INDIVIDUAL PRESENTING METABOLIC SYNDROME: AN EXERGETIC ANALYSIS

Submission Author: João Vitor Garcia , AL
Co-Authors: João Vitor Garcia, Weliton Martins, TAYNARA LAGO, Adriano Marques
Presenter: João Vitor Garcia

doi://10.26678/ABCM.COBEM2023.COB2023-1742

 

Abstract

Thermodynamics can be applied to estimate the efficiency of metabolic processes in the human body and its relationship with life expectancy. Metabolic syndrome, a metabolic disorder that includes insulin resistance and is associated with various comorbidities, primarily obesity, has a direct impact on life expectancy due to its metabolic alterations. Therefore, the present article aims to study the effects of these modifications in individuals with metabolic syndrome and their relationship with life expectancy. For this purpose, a mathematical model was sought in the literature to evaluate processes in the human body using exergy parameters. The model divided the body into two control volumes, representing the various systems of the body and cellular metabolism. The destroyed exergy was evaluated to determine the exergetic age, and a simplified thermal model with four different types of tissues was analyzed. Simulations were performed with three distinct groups of individuals (control, moderately obese, and obese) to evaluate the impact of metabolic syndrome on life expectancy. The results show a significant increase in the rate of destroyed exergy as the individual's mass increases, with a higher rate in the obese group. However, when considering the rate of destroyed exergy per unit mass, the obese group has a lower rate than the moderately obese and control groups, suggesting that the increase in the individual's mass outweighs the exergy expenditure, which is consistent with previous studies. When applying the model to cases of weight loss or weight gain, it was observed that these individuals tend towards a similar value, with only a 1.8% difference when considering the accumulated exergy per unit mass, indicating that the earlier these changes occur, the greater the impact on the individual's life expectancy. It is concluded that, by analyzing the curves of accumulated exergy, obese individuals would take longer to reach the limit value of accumulated destroyed exergy, suggesting a longer life expectancy. However, the discrepancy with reality may be related to metabolic alterations resulting from metabolic syndrome and its effects on physiological functions of the human body. Furthermore, remaining in the condition of obesity can reduce life expectancy by up to 15 years. This highlights the importance of prevention and treatment of obesity and other factors of metabolic syndrome.

Keywords

Exergetic Analysis, Entropy, metabolism, Metabolic syndrome, Rate of living theory

 

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