Eventos Anais de eventos
ENEBI 2018
6º Encontro Nacional de Engenharia Biomecânica
Characterization of mechanical behavior of biodegradable polymer polycaprolactone after hydrolytic degradation
Submission Author:
André Vieira , SP
Co-Authors:
Marcos Vinícios Hiroshi Taguti, Adriano Françoso, André Vieira
Presenter: Marcos Vinícios Hiroshi Taguti
doi://10.26678/ABCM.ENEBI2018.EEB18-0049
Abstract
In tissue engineering, the use of scaffolds for non-vascularized tissue regeneration is a recent application, which presents a more satisfactory result when these are naturally eroded and assimilated during tissue regeneration. In the process of scaffolds design, to select an optimal biodegradable material, one must know the mechanical behavior during degradation. Thus, the present work shows a methodology to characterize the mechanical behavior during degradation of one of these biodegradable polymers, the polycaprolactone (PCL). Their mechanical characteristics are interesting in many soft tissue applications. To characterize the mechanical behavior during degradation, samples were manufactured by Fused Deposition Modelling (FDM) technology, which is closely linked with the personalized scaffolds fabrication and is able to create complex geometries. These samples were degraded at different stages of time in a thermostatic bath at 37º and pH 7,4. Finally, samples were tensile tested. The results showed an increase of stiffness and tensile strength.
Keywords
Biodegradable polymers, Hydrolytic degradation, Polycaprolactone, Mechanical Characterization
