Eventos Anais de eventos
COBEM 2021
26th International Congress of Mechanical Engineering
Verification of numerical models of hemolytic index based on Eulerian and Lagrangian approaches in FDA (Food and Drug Administration) benchmarks
Submission Author:
Mirella Gibson , MG
Co-Authors:
Mirella Gibson, Mário Silva, Rudolf Huebner
Presenter: Mirella Gibson
doi://10.26678/ABCM.COBEM2021.COB2021-1910
Abstract
The change in flow caused by the insertion of clinical devices modifies the shear stress acting under blood cells, which can trigger the hemolysis process. This hemodynamic effect is related to shear stress and its exposure time, which can be modeled by a mathematical model called Hemolytic Index (HI). In this context, the computational fluid dynamics can be applied to understand the hemodynamic effects, using two approaches: Eulerian and Lagrangian. In order to compare these approaches, the study developed here reproduces the methodologies of FDA (Food and Drug Administration) Benchmarks in numerical flow models in medical devices. Based on experimental data from the literature, it was possible to verify the mathematical models used for HI. The experiment carried out consists of a numerical simulation of the blood porcine flow in a nozzle geometry, in turbulent regime for sudden-contraction inlet and gradual cone inlet conditions with different mass flow rates. From the results, it was observed high relative errors when comparing both approaches with the experiment, with greater discrepancy in relation to the sudden-contraction inlet situation. Therefore, the mathematical models presented are simple for analyzing medical devices with complex flow, in which the shear stress varies along the trajectory lines.
Keywords
Computational fluid dynamics (CFD), Hemolysis, Eulerian Approach, Lagrangian approach
