Eventos Anais de eventos
COBEM 2021
26th International Congress of Mechanical Engineering
HEMODYNAMICS STUDY OF BLOOD AND SENSITIVITY ANALYSIS IN BIOLOGICAL STRUCTURE FOR CASES OF ISCHEMIC STROKE
Submission Author:
Tarik Hazem Ashmawi , SP
Co-Authors:
Tarik Hazem Ashmawi, João Pedro Oliveira Donato, Alessandro Baccaro, Beatriz Ikeda Alcatrão, Bruno Chieregatti, Carlos Baccin , João de Sá Brasil Lima
Presenter: Tarik Hazem Ashmawi
doi://10.26678/ABCM.COBEM2021.COB2021-1275
Abstract
Abstract: According to the Brazilian Ministry of Health, over 101 thousand deaths registered in 2020 were caused by stroke, a disease that can be classified as hemorrhagic or ischemic with the last one being the cause of over 80% of all cases. For such reason it shall be the topic of focus of this study. The ischemic stroke is consequence of a blockage inside one of the blood vessels leading to the brain, decreasing blood flow which may result in lack of oxygen and nutrients to the cerebral tissue. The main causes of an ischemic stroke are the presence of either an atherosclerotic plaque, composed of the accumulation of lipids or fibrous matter; or a thrombus, the latter occurring in regions already obstructed by the former and being made of blood clot particles. Seeking to further comprehend human health, medicine and engineering have been working together, for example, to study biological flows. Such union between the two areas paves the way for more effective solutions. Ischemic stroke itself is an example of a disease that is under study in order to make its identification more agile, as well as its stage and provide increasingly less invasive prophylaxis. Thus, the main goal of this work is directed towards obtaining the relevant parameters involved in the hemodynamics within the internal carotid artery (ICA) in the cranial section affected by an ischemic stroke. Blood flow will be analyzed using a computer fluid dynamics (CFD) simulation with the Ansys Fluent software to solve the three-dimensional Navier–Stokes equation, while vessel geometry will be modeled and based on real data. Different instances will be studied: first a healthy artery and then one with varying degrees of stenosis from 50% to 90% of obstruction. Through these stenosis variations, existing correlations between some parameters will be analyzed through a sensitivity analysis, such as: pressure gradient, wall shear stress and Womersley number. A comparative analysis will be made between the standard Newtonian blood model and non-Newtonian Carreau-Yasuda model, as well as evaluating the uniform velocity and pulsatile profiles.
Keywords
Ischemic stroke, CFD simulation, Internal carotid artery, Stenosis, hemodynamics
