Eventos Anais de eventos
COBEM 2019
25th International Congress of Mechanical Engineering
COMPARING MONTE CARLO WITH DISCRETE ORDINATES METHOD FOR SILICA-CORE GOLD NANOSHELLS ASSISTED LASER PHOTOTHERMAL THERAPY
Submission Author:
Anderson Nunes de Sousa , RN
Co-Authors:
Anderson Nunes de Sousa, Andre Maurente
Presenter: Anderson Nunes de Sousa
doi://10.26678/ABCM.COBEM2019.COB2019-2301
Abstract
Photothermal Therapy (PTT) uses electromagnetic radiation to increase tissue temperature and kill targeted cancerous cells. In this work, silica-core gold nanoshells are the photon absorbers that convert the electromagnetic energy into heat. The main objective is to compare Monte Carlo (MC) method with Discrete Ordinates (DO) method for the solution of the Radiative Transfer Equation (RTE) in an one-dimensional bioheat transfer model composed of five layers, one of them with a cancerous tumor and silica-core gold nanoparticles, irradiated by a near-infraed (NIR) laser. The overall maximum difference of peak temperature was equal to 0.085053 °C at 35 s of simulated time, and the maximum difference of tissue depth for peak temperature was equal to 0.0125 mm. Results demonstrated both methods performing similarly for this specific task.
Keywords
Monte-Carlo simulation, Pennes´ Equation, bioheat transfer, Skin Cancer, Gold nanoparticles
