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ENCIT 2020
18th Brazilian Congress of Thermal Sciences and Engineering
Comparative Study Between Eulerian and Lagrangian Approaches for the Analysis of Hemolytic and Platelet Lysis Index with Couette Flow
Submission Author:
Mirella Gibson , MG
Co-Authors:
Mirella Gibson, Mário Silva, Jonathas Haniel, Rudolf Huebner
Presenter: Mirella Gibson
doi://10.26678/ABCM.ENCIT2020.CIT20-0584
Abstract
The applications of clinical cardiac assistance systems, when in contact with the bloodstream, modify the flow in its insertion region. These changes can trigger harmful processes like hemolysis and thrombosis. The hemodynamic effects are related to shear stress and exposure time acting on blood cells. Computational fluid dynamics has been widely applied to understand the mechanics of fluids behind blood damage through two approaches: Eulerian and Lagrangian. The Eulerian approach has raised doubts in academic community due to some inherent limitations of such methodology. On the other hand, studies based on the Lagrangian approach have developed different methodologies in an attempt to better understand the mechanism of hemolysis and thrombus formation due to the contact of clinical instruments with blood. In order to compare these methods, this work reproduces the Couette flow for analysis of hemolytic and platelet lysis index. The reproduced experiment consists of a numerical simulation of blood flow in laminar regime. The results were compared with experimental data from the literature, and both methods showed proximity for a simple flow.
Keywords
COUETTE FLOW, Hemolysis, Thrombosis, Eulerian Approach, Lagrangian approach
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