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ENCIT 2020
18th Brazilian Congress of Thermal Sciences and Engineering
PDMS MICROCAPSULES FOR TRIGGERED RELEASE BY OSMOTIC PRESSURE
Submission Author:
Célia Melo , RJ , Brazil
Co-Authors:
Célia Melo, Raphael Chalhub Oliveira Spinelli Ribeiro, Bruna Leopercio, Marcio CARVALHO
Presenter: Célia Melo
doi://10.26678/ABCM.ENCIT2020.CIT20-0524
Abstract
Monodispersed microcapsules can be produced from double emulsions templates and can be used as vehicles for triggered release in different applications. In the present work, microcapsules with a PDMS shell were produced using a microfluidic device, which combines co-flow and flow-focusing in coaxial glass-capillaries. For the controlled release, osmotic pressure was used as trigger. The PDMS microcapsules were placed in mediums with different osmolality and they were monitored using a confocal microscope. Confocal laser scanning microscopy allows the 3D reconstructions of the capsules to quantify their volume, as well as to determine the capsule’s shape. The results point that when the microcapsules are exposed to a hypotonic medium, they swell; whereas, when they are suspended in a hypertonic medium, they shrink and the shell eventually buckles. This work shows that osmolality can work as a trigger for content release and that the dynamics of the release process can be controlled by the osmolality of the medium and capsule properties. This information can be helpful for the use of PDMS microcapsules delivering active compounds for a broad range of applications.
Keywords
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