INFORMATIVO ABCM Nº 37/2021

INFORMATIVO ABCM Nº 37/2021

Semana de 3 a 9 de Dezembro de 2021

 

 

 

 

Seminário ABCM de Fenômenos Não Lineares

Fonte: Prof. Americo Cunha (UERJ)

 

 

O Comitê de Fenômenos Não Lineares e Caóticos está organizando a série “Seminário ABCM de Fenômenos Não Lineares”, congregando palestras em temas alinhados com o escopo de atuação do comitê. 

 

Teremos o primeiro seminário na próxima semana, dia 8/12/2021 às 18h, sendo organizado pelo Programa de Pós-graduação em Engenharia Mecânica da UERJ.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Título: Multiscale, Multiphysical Phenomena in Arterial Remodeling

Palestrante: Marisa Bazzi (Department of Chemical Engineering and Material Science, University of Minnesota)

Abstract:

Ascending thoracic aortic aneurysms (ATAAs) are bulging enlargements of the aorta in the section just after it exits the heart. They affect approximately 15,000 people in the US per year and can be fatal in 80% of the cases when ruptured. On the other hand, surgical repair of the aorta has its own risks and may not be necessary for many patients. Surgical intervention criteria are defined primarily in terms of the maximum diameter and growth rate, but it has been shown that about 60% of the patients present complications before the intervention criteria are reached, and about 40% of patients who meet the criteria for surgery do not, in fact, experience complications even when surgery is not performed. Clearly, a better way to predict the long-term outcome of an ATAA is needed. Ph.D. candidate Marisa Bazzi, uses a combination of experimental and computational techniques to explore the mechanisms of ATAA formation, growth, and failure. For the talk, Marisa will discuss her work exploring how macroscale biofluidic, geometrical and biomechanical factors affect the microscale growth and remodeling (G&R) process of the aortic tissue leading to the formation of ATAA. She will describe her combined experimental and computational approach using data from mice and humans to study the relevance of the main biomarkers on the ATAA outcome. She will then shift to her future work and discuss her planned creation of a fluid-structure- remodeling computational platform to study ATAA and other diseases that involve aberrant remodeling of the arterial tree.

 

 

 

Marisa is currently a 4th year PhD candidate in the Chemical Engineering and Material Science at the University of Minnesota, with bachelor and master’s degree in Mechanical Engineering from the Pontifical Catholic University of Rio de Janeiro (PUC-Rio). Her PhD research focus on using biomedical/mechanical engineering principles in combination with computer science techniques to understand cardiovascular diseases better.

 

 

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