COBEM99

S2 Bioengenharia e Qualidade de Vida

Title:

ESTUDO DE BIOCERÂMICAS COMO DEPÓSITO PARA LIBERAÇÃO CONTROLADA DE FÁRMACOS

Summary :

STUDY OF BIOCERAMIC AS DRUG-DELIVERY SYSTEM FOR ANTIBIOTICS ABSTRACT. THIS WORK STUDIED THE INCORPORATION AND RELEASE OF THE ANTIBIOTIC LOADED BY A BIOCERAMIC OF PHOSPHATE OF CALCIUM (OSTEOSYNTÒ). THE AMOUNT OF DRUG INCORPORATED IN THE BIOCERAMIC WAS BASED ON ITS TOTAL WEIGHT TO BE USED. THE ANTIBIOTIC PERCENTAGE USED IN THE EXPERIMENT WAS OF 10% IN RELATION TO THE WEIGHT. FOR THE GENTAMICIN IT WAS VERIFIED THAT THERE WAS, IN THE INTERVAL OF TIME OF 72 HOURS, OBTAIEND RELEASE OF 90% OF THE INCORPORATE ANTIBIOTIC. KEY WORDS: DRUG-DELIVERY, GENTAMICIN, OSTEOMYELITIS, BIOCERAMIC.

Author :

Caballero, Eduardo 0
Pinotti, Marcos 0
Wykrota, Francisco H. L.
Wykrota, Leonardo L.

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